March 9, 2021

Serological Evidence of Human Infection with SARS-CoV-2: A Systematic Review and Meta-Analysis

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): antibodies, immunity

• Seroprevalence of SARS-CoV-2-specific antibodies varied dramatically across WHO regions, according to a systematic review and meta-analysis including over 5 million participants from 400 serosurveys. The Southeast Asia region had the highest seroprevalence (20%), while the Western Pacific region, including Australia and New Zealand, had the lowest (1.7%). In a subset of serosurveys with higher quality data, seroprevalence in close contacts (18%) and high-risk healthcare workers (17%) was higher compared to low-risk healthcare workers (4%) and the general population (8%).

Chen et al. (Mar 8, 2021). Serological Evidence of Human Infection with SARS-CoV-2: A Systematic Review and Meta-Analysis. The Lancet Global Health. https://doi.org/10.1016/S2214-109X(21)00026-7