Alliance for Pandemic Preparedness

March 11, 2021

Follow-up Testing of Borderline SARS-CoV-2 Patients by RRT-PCR Allows Early Diagnosis of COVID-19

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  • Follow-up testing of “borderline” PCR test results within 96 hours occasionally identified additional positive results, according to a retrospective analysis of over 30,000 SARS-CoV-2 PCR test results (1,092 positive). Of the 204 borderline results, which had viral amplification just below the positivity threshold (>25 viral copies/mL), 107 were re-tested and 10 were found positive, representing 0.92% of overall positive results. 

Boeckmans et al. (Feb 18, 2021). Follow-up Testing of Borderline SARS-CoV-2 Patients by RRT-PCR Allows Early Diagnosis of COVID-19. Diagnostic Microbiology and Infectious Disease. https://doi.org/10.1016/j.diagmicrobio.2021.115350