Alliance for Pandemic Preparedness

March 15, 2021

Age Cohorts Stratified According to Age-Distributions of COVID-19 Morbidity Statistics Identify Uniquely Age-Dependent CD3 + CD8 + T-Cell Lymphocytopenia in COVID-19 Patients without Comorbidities on Admission

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  • SARS-CoV-2 infection was associated with age-dependent reductions in CD8+ T cell count in a retrospective study of 447 individuals stratified by five age-group cohorts spanning ages 2 to 79. CD4+ T cell, B cell, and natural killer cell counts did not differ between age strata. Plasma C-reactive protein concentrations increased with age.

Jin et al. (Mar 10, 2021). Age Cohorts Stratified According to Age-Distributions of COVID-19 Morbidity Statistics Identify Uniquely Age-Dependent CD3 + CD8 + T-Cell Lymphocytopenia in COVID-19 Patients without Comorbidities on Admission. Aging. https://doi.org/10.18632/aging.202691