Alliance for Pandemic Preparedness

March 15, 2021

Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks — Connecticut, December 2020–February 2021

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  • Partial vaccination with the Pfizer-BioNTech COVID-19 vaccine (from >14 days after dose 1 through 7 days after dose 2) was found to be to 63% effective against SARS-CoV-2 infection among residents of two skilled nursing facilities in Connecticut that experienced outbreaks from December 2020 – February 2021. Vaccine efficacy was similar (60%) when residents with prior SARS-CoV-2 infection were excluded. The retrospective cohort study determined that 97 cases of SARS-CoV-2 infection occurred during the outbreaks, including 40 (41%) at facility A and 57 (59%) at facility B. By the end of the study, most residents (304, 66%) received 2 vaccine doses, 72 (16%) received only 1 dose, and 87 (19%) were not vaccinated. 

Britton et al. (Mar 15, 2021). Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks — Connecticut, December 2020–February 2021. MMWR. Morbidity and Mortality Weekly Report. https://doi.org/10.15585/mmwr.mm7011e3