March 17, 2021

Real-World Experience of SARS-CoV-2 Antibody Assays in UK Healthcare Workers

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): testing

• Among health care workers in the UK, Abbott and Roche antibody assays showed low sensitivity for detecting individuals with previous PCR-confirmed infection. In a cohort study conducted at 2 medical centers in the UK, the Abbott antibody assay had a sensitivity (proportion with a positive antibody test result in those with previous PCR-confirmed infection) of 40% and the Roche assay had a sensitivity of 81%. Antibody seroprevalence was 8% in the cohort tested with the Abbott assay and 13% for the cohort tested with the Roche assay. Testing was conducted ~60-90 days after infection.

Robinson et al. (Mar 16, 2021). Real-World Experience of SARS-CoV-2 Antibody Assays in UK Healthcare Workers. Clinical Medicine. https://doi.org/10.7861/clinmed.2020.1007