Alliance for Pandemic Preparedness

March 18, 2021

Frailty as a Predictor of Mortality among Patients with COVID-19: A Systematic Review and Meta-Analysis

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  • COVID-19 patients with frailty had a 2.5-fold higher risk of dying compared to those without frailty, according to a systematic review and meta-analysis of 15 studies including 23,944 COVID-19 patients. Subgroup analyses of studies with hospitalized patients (n=8 studies) and nursing home residents (n=2) showed that risk of dying among patients with frailty was 2.6-fold and 2.1-fold higher, respectively. Patients with frailty were at higher risk of mortality regardless of the frailty assessment tool used.

Zhang et al. (Mar 17, 2021). Frailty as a Predictor of Mortality among Patients with COVID-19: A Systematic Review and Meta-Analysis. BMC Geriatrics. https://doi.org/10.1186/s12877-021-02138-5