Alliance for Pandemic Preparedness

March 23, 2021

Association of Age With SARS-CoV-2 Antibody Response



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  • SARS-CoV-2 antibody responses are distinct in different age groups, according to a cross-sectional study of a New York City hospital using 31,426 SARS-CoV-2 antibody test results from pediatric and adult patients.  IgG levels were negatively correlated with age in the pediatric population (r = -0.45, P < .001), but moderately positively correlated with age in adults (r = 0.24, P < .001). Patients aged 19 to 30 years exhibited the lowest IgG levels, whereas adolescents and children had higher antibody levels.

Yang et al. (Mar 22, 2021). Association of Age With SARS-CoV-2 Antibody Response. JAMA Network Open.