Alliance for Pandemic Preparedness

March 29, 2021

Hemodialysis Patients Show a Highly Diminished Antibody Response after COVID-19 MRNA Vaccination Compared to Healthy Controls

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  • [Pre-print, not peer-reviewed] Patients receiving hemodialysis had significantly lower anti-SARS-CoV-2 antibody titers than healthy controls 21 days after vaccination with the Pfizer-BioNTech vaccine (171 U/ml versus 2500 U/ml, respectively), according to a prospective cohort study (n = 81 patients, 80 controls). There was no correlation between antibody responses to the Hepatitis B vaccine and the SARS-CoV-2 vaccine. 

Simon et al. (Mar 26, 2021). Hemodialysis Patients Show a Highly Diminished Antibody Response after COVID-19 MRNA Vaccination Compared to Healthy Controls. Pre-print downloaded Mar 29 from https://doi.org/10.1101/2021.03.26.21254259