March 29, 2021

Interim Estimates of Vaccine Effectiveness of BNT162b2 and MRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers — Eight U.S. Locations, December 2020–March

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): vaccine

• The mRNA vaccines (Pfizer/BioNTech and Moderna) were 90% effective at preventing SARS-CoV-2 infection after full immunization (≥14 days after second dose) and 80% after partial immunization (≥14 days after first dose but before second dose), according to interim estimates among 3,950 healthcare personnel, first responders, and other essential and frontline workers in multiple locations across the US. Study participants completed weekly SARS-CoV-2 testing for 13 consecutive weeks, from December 14-18, 2020 to March 13, 2021. 

Thompson et al. (Mar 29, 2021). Interim Estimates of Vaccine Effectiveness of BNT162b2 and MRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers — Eight U.S. Locations, December 2020–March. MMWR. Morbidity and Mortality Weekly Report. https://doi.org/10.15585/mmwr.mm7013e3