Alliance for Pandemic Preparedness

April 1, 2021

Post-Covid Syndrome in Individuals Admitted to Hospital with Covid-19: Retrospective Cohort Study

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  • Individuals discharged following hospitalization for COVID-19 were 4 and 8 times more likely to be readmitted and to die compared to controls matched for personal and clinical characteristics. In this retrospective cohort study, 47,780 patients with COVID-19 discharged by August 2020 were matched to a pool of about 50 million people in England. Nearly a third of individuals in the discharged cohort were readmitted, and more than 1 in 10 died over a mean follow-up of 140 days. Compared to controls, patients with COVID-19 had significantly higher rates of respiratory disease, diabetes, and cardiovascular disease. Patients with COVID-19 aged 70 or older (vs younger) and those in ethnic minority groups as (vs white) were more likely to experience multiorgan dysfunction.

Ayoubkhani et al. (Mar 31, 2021). Post-Covid Syndrome in Individuals Admitted to Hospital with Covid-19: Retrospective Cohort Study. BMJ. https://doi.org/10.1136/bmj.n693