Alliance for Pandemic Preparedness

April 2, 2021

COVID-19 in Individuals with Sickle Cell Disease/Trait Compared with Other Black Individuals

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  • Persons diagnosed with COVID-19 and sickle cell disease (SCD) (n=312) were 2-times as likely to be hospitalized and develop pneumonia and 3-times as likely to develop pain compared to a propensity matched cohort of Black persons diagnosed with COVID-19 but without SCD or sickle cell trait (SCT). No significant differences were observed in case mortality between the two groups. No significant differences in COVID-19 outcomes were observed between persons diagnosed with COVID-19 and who have sickle cell trait (SCT) (n=449) and a propensity matched cohort of Black persons diagnosed with COVID-19 but without SCD/SCT.

Singh et al. (Apr 1, 2021). COVID-19 in Individuals with Sickle Cell Disease/Trait Compared with Other Black Individuals. Blood Advances. https://doi.org/10.1182/bloodadvances.2020003741