April 5, 2021

Antibody Responses to the BNT162b2 MRNA Vaccine in Individuals Previously Infected with SARS-CoV-2

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity, vaccine

• Among healthcare workers in California who received the Pfizer-BioNTech vaccine (n = 1,090), spike-specific IgG antibody levels and ACE2 antibody binding inhibition responses were similar between individuals who had been previously infected with SARS-CoV-2 and received a single dose (n = 35), and those who had no prior infection and received both vaccine doses (n = 228). The study measured participants’ antibody levels at three time points: before or up to 3 days after dose 1; within 7–21 days after dose 1; and within 7–21 days after dose 2.

Ebinger et al. (Apr 1, 2021). Antibody Responses to the BNT162b2 MRNA Vaccine in Individuals Previously Infected with SARS-CoV-2. Nature Medicine. https://doi.org/10.1038/s41591-021-01325-6