Alliance for Pandemic Preparedness

April 14, 2021

Adverse Events in Healthcare Workers after the First Dose of ChAdOx1 NCoV-19 or BNT162b2 MRNA COVID-19 Vaccination: A Single Center Experience

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  • A study of 1st dose post-vaccination adverse events in Korean healthcare workers at a single hospital (N=1,483) found that adverse events were significantly more common in recipients of the Oxford/AstraZeneca vaccine (N=1,403) than the Pfizer-BioNTech vaccine (N=80). The adverse events included injection-site pain (78% vs. 51%), myalgia (61% vs. 11%), fatigue (52% vs. 8%), headache (47% vs. 8%), and fever (36 % vs. 5%) (p< 0.001 for all). Young healthcare workers were more likely to experience adverse events and most adverse events were mild or moderate.

Kim et al. (Apr 2021). Adverse Events in Healthcare Workers after the First Dose of ChAdOx1 NCoV-19 or BNT162b2 MRNA COVID-19 Vaccination: A Single Center Experience. Journal of Korean Medical Science. https://doi.org/10.3346/jkms.2021.36.e107