Alliance for Pandemic Preparedness

April 21, 2021

Post-COVID-19 Syndrome in Outpatients a Cohort Study

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  • [Pre-print, not peer-reviewed] In a prospective cohort of symptomatic outpatients undergoing SARS-CoV-2 PCR testing in Switzerland (n= 507), 53% of patients with SARS-CoV-2 infection reported persistent symptoms between 3 and 10 months after diagnosis compared to 37% of patients who tested negative. About 20% of patients who tested positive consulted a physician for persistent symptoms, and the most common symptoms were fatigue (32%), smell or taste disorder (22%), dyspnea (16%), headache (12%), memory impairment 135 (11%), hair loss (10%), and sleep disorder (10%). Among patients who tested positive for SARS-CoV-2, female sex (aOR = 1.7) and overweight/obesity (aOR = 1.7) predicted persistent symptoms.  

Desgranges et al. (Apr 20, 2021). Post-COVID-19 Syndrome in Outpatients a Cohort Study. Pre-print downloaded Apr 21 from https://doi.org/10.1101/2021.04.19.21255742