Alliance for Pandemic Preparedness

April 28, 2021

Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged =65 Years — United States, January–March 2021

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  • Among adults age 65 and older (n = 417), mRNA vaccines were 94% effective against hospitalization for COVID-19 among fully vaccinated individuals, and 64% effective among partially-vaccinated individuals, according to data from US hospitals during January-March 2021. In the study, Pfizer and Moderna vaccines were equally represented, and approximately half of participants were over the age of 75, which the authors argue provides evidence for the real-world effectiveness of these vaccines in older adults.

Tenforde et al. (Apr 28, 2021). Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged =65 Years — United States, January–March 2021. MMWR. Morbidity and Mortality Weekly Report. https://doi.org/10.15585/mmwr.mm7018e1