May 4, 2021

Human Organoid Systems Reveal in Vitro Correlates of Fitness for SARS-CoV-2 B.1.1.7

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics, variants

• [Pre-print, not peer-reviewed] In an in vitro human organoid system, the SARS-CoV-2 B.1.1.7 variant was shown to produce higher levels of infectious virus late in infection and higher replicative fitness in human airway, alveolar, and intestinal organoid models compared to the ancestral strain.

Lamers et al. (May 3, 2021). Human Organoid Systems Reveal in Vitro Correlates of Fitness for SARS-CoV-2 B.1.1.7. Pre-print downloaded May 4 from https://doi.org/10.1101/2021.05.03.441080