May 5, 2021

Persistent Neuropsychiatric Symptoms after COVID-19 a Systematic Review and Meta-Analysis

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics, sequelae

• [Pre-print, not peer-reviewed] In a systematic review and meta-analysis of neuropsychiatric symptoms in COVID-survivors (51 studies of 18,917 COVID-19 survivors), sleep disturbance was the most common neuropsychiatric symptom with a pooled prevalence of 27%, followed by fatigue (24%), objective cognitive impairment (also known as brain fog, 20%), anxiety (19%), and post-traumatic stress (16%). Mean duration of follow-up was 77 days after symptom onset. There was little to no evidence that symptom prevalence varied across hospitalization status, disease severity, or duration of follow-up.

Badenoch et al. (May 4, 2021). Persistent Neuropsychiatric Symptoms after COVID-19 a Systematic Review and Meta-Analysis. Pre-print downloaded May 5 from  https://www.medrxiv.org/content/10.1101/2021.04.30.21256413v1