May 6, 2021

Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): vaccines

• Vaccination with the Pfizer-BioNTech vaccine was associated with a 72% lower incidence of a positive SARS-CoV-2 PCR result during routine weekly screening for asymptomatic infection among employees of St. Jude Children’s Research Hospital between December 2020 to March 2021 and a greater than 90% reduction in PCR positivity among fully vaccinated individuals. Incidence of asymptomatic infection during screening was 42% lower among vaccinated individuals compared to unvaccinated individuals within the first 11 days after the first dose, 65% lower within the first 7 days after the second dose, and 90% lower 7 days or more after the second the dose. No symptomatic infections were detected among vaccinated individuals more than 7 days after the second dose.

Tang et al. (May 6, 2021). Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination in a Routinely Screened Workforce. JAMA. https://jamanetwork.com/journals/jama/fullarticle/2779854