May 13, 2021

Heterogeneous Magnitude of Immunological Memory to SARS-CoV-2 in Recovered Individuals

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

• SARS-CoV-2-specific cellular and humoral immune responses were maintained up to 5 months post infection in a cohort of professional soccer players in Italy (n=30). 20% of participants displayed weaker immune responses over time, indicating heterogeneity in magnitude of immunological memory. Stronger cellular immune response was associated with symptomatic infection as indicated by higher levels of SARS-CoV-2-specific CD4+ T cells.

Mazzoni et al. (May 6, 2021). Heterogeneous Magnitude of Immunological Memory to SARS-CoV-2 in Recovered Individuals. Clinical & Translational Immunology. https://doi.org/10.1002/cti2.1281