May 13, 2021

Persistence of Antibody and Cellular Immune Responses in COVID-19 Patients over Nine Months after Infection

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): immunity

• Anti-SARS-CoV-2 IgG, IgM, and neutralizing antibodies against the spike and nucleocapsid proteins were detected in approximately 90% of participants in a cross-sectional study of 59 mostly mild COVID-19 patients after a median of 317 days (range 257 – 343) since symptom onset, while roughly 60% of patients had anti-receptor binding domain (RBD) IgG antibodies. In terms of cellular immune responses, SARS-CoV-2-specific memory B and T cells were detectable in over 70% of patients.

Yao et al. (May 12, 2021). Persistence of Antibody and Cellular Immune Responses in COVID-19 Patients over Nine Months after Infection. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiab255