May 14, 2021

Ivermectin in Combination with Doxycycline for Treating COVID-19 Symptoms: A Randomized Trial

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): treatment

• A randomized, blinded, placebo-controlled trial of ivermectin combined with doxycycline for patients with mild-to-moderate COVID-19 symptoms (N=400) found that treated patients had a shorter median time to recovery (7 vs. 9 days) and were more likely to be SARS-CoV-2 negative by RT-PCR at two weeks follow-up. However, the investigators note that the majority of study participants were <40 years of age, and that in subgroup analysis patients with severe disease did not differ in their disease response to treatment compared to placebo. 

Mahmud et al. (May 2021). Ivermectin in Combination with Doxycycline for Treating COVID-19 Symptoms: A Randomized Trial. The Journal of International Medical Research. https://doi.org/10.1177/03000605211013550