May 17, 2021

Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca Vaccines on Covid-19 Related Symptoms, Hospital Admissions, and Mortality in Older Adults in England: Test Negative Case-Control Study

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): vaccine

• A case-control study of the effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines among adults aged 70 and older (n = 156,930) found that one dose of either vaccine was about 80% effective at preventing hospital admission with COVID-19, and a single dose of Pfizer-BioNTech was 85% effective at preventing death (follow-up was insufficient to assess the effect of Oxford-AstraZeneca on mortality), with protection maintained for at least 6 weeks. 

Lopez Bernal et al. (May 13, 2021). Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca Vaccines on Covid-19 Related Symptoms, Hospital Admissions, and Mortality in Older Adults in England: Test Negative Case-Control Study. BMJ. https://doi.org/10.1136/bmj.n1088