Alliance for Pandemic Preparedness

May 26, 2021

Ivermectin for the Treatment of COVID-19 A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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  • [Pre-print, not peer-reviewed] A systematic review and meta-analysis (n = 10 studies, n = 1,173 patients) of randomized controlled trials found that the use of ivermectin for treatment of COVID-19 did not reduce all-cause mortality, length of hospitalization, adverse events, or viral clearance. Trials of ivermectin for the treatment of mild to moderate COVID-19 in low- and middle-income countries (N=9) and Spain were included. The authors note that the quality of evidence was low or very low for all outcomes but concluded their results do not support the use of ivermectin for treatment of COVID-19.

Roman et al. (May 25, 2021). Ivermectin for the Treatment of COVID-19 A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pre-print downloaded May 26 from https://doi.org/10.1101/2021.05.21.21257595