June 3, 2021

Pfizer-BioNTech COVID-19 Vaccine Tolerance in Allergic versus Non-Allergic Individuals

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): adverse effects, vaccination, vaccine side effects

• The Pfizer-BioNTech vaccine elicited worse local and systemic reactions among individuals with a history of allergy in an online survey of vaccinated medical professionals in Poland (n=1,808). However, no severe allergic reactions were reported. Local redness (17% vs 11%), pain (86% vs 80%), and swelling (19% vs 13%) after the first dose and vomiting (3% vs 1%) and joint pain (32% vs 26%) after the second dose were more frequent in allergic individuals. Other common symptoms such as fever and fatigue were not significantly different between the two groups.

Nittner-Marszalska et al. (May 25, 2021). Pfizer-BioNTech COVID-19 Vaccine Tolerance in Allergic versus Non-Allergic Individuals. Vaccines. https://doi.org/10.3390/vaccines9060553