June 7, 2021

Naturally Acquired SARS-CoV-2 Immunity Persists for up to 11 Months Following Infection

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): antibodies, immunity

• A longitudinal study of convalescent plasma donors (n = 228) detected anti-SARS-CoV-2 antibodies in 97% of donors at initial presentation, and found that 91.4% of the 116 donors presenting for repeat timepoints had detectable IgG levels up to 11 months post-symptom recovery. The VITROS® Anti-SARS-CoV-2 Total and IgG assays, and an in-house fluorescence reduction neutralization assay, were used to test samples. 63% of donors had detectable neutralizing titers, while 25% had neutralizing levels that dropped to an undetectable titer over time. The authors suggest their results indicate that immunological memory lasts for at least 11 months after recovery from COVID-19.

De Giorgi et al. (June 2021). Naturally Acquired SARS-CoV-2 Immunity Persists for up to 11 Months Following Infection. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiab295