May 27, 2021

Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): clinical characteristics, sequelae

• A systematic review of 45 studies including 9,751 participants with COVID-19 found the most frequent persistent symptoms (≥60 days) included shortness of breath (median 36% of participants in 26 studies), fatigue (median 40% in 25 studies), and sleep disorder (median 30% in 8 studies). A median of 73% of participants in 16 studies of mostly hospitalized patients reported at least 1 persistent symptom. Two thirds of included studies reported mean or median age of <60 years. Significant variations in study design limited direct comparability and combinability.

Nasserie et al. (May 26, 2021). Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2021.11417