June 4, 2021

Inhaled Corticosteroids Do Not Adversely Impact Outcomes in COVID-19 Positive Patients with COPD: An Analysis of Cleveland Clinic’s COVID-19 Registry

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): treatment

• A large retrospective cohort study of persons with chronic obstructive pulmonary disease (COPD) (N=27,810) found that inhaled corticosteroid therapy did not increase COVID-19 related healthcare utilization or mortality. There were no statistically significant differences observed in hospitalization, ICU admission, endotracheal intubation, mechanical ventilation, or mortality among persons with a positive SARS-COV-2 test after adjusting for demographics, month of SARS-CoV-2 testing, and comorbidities known to be associated with severe COVID-19. The authors report that these findings should encourage clinicians to continue inhaled corticosteroid therapy for persons with COPD during the COVID-19 pandemic.

Sen et al. (June 3, 2021). Inhaled Corticosteroids Do Not Adversely Impact Outcomes in COVID-19 Positive Patients with COPD: An Analysis of Cleveland Clinic’s COVID-19 Registry. PLOS ONE. https://doi.org/10.1371/journal.pone.0252576