Alliance for Pandemic Preparedness

June 9, 2021

Functional Characterization of SARS-CoV-2 Vaccine Elicited Antibodies in Immunologically Nave and Pre-Immune Humans

Category:

Topic:

Keywords (Tags): , ,

  • [Pre-print, not peer-reviewed] The Pfizer-BioNTech vaccine elicited higher neutralizing and anti-SARS-CoV-2 antibody binding responses in individuals with prior infection (n=32) compared to those without prior infection (n=20). The second vaccine dose did not significantly increase neutralizing or binding antibody levels in individuals with prior infection, whereas the second dose was required to induce antibody responses in nearly half of infection-naïve individuals. 

Forgacs et al. (May 31, 2021). Functional Characterization of SARS-CoV-2 Vaccine Elicited Antibodies in Immunologically Nave and Pre-Immune Humans. Pre-print downloaded Jun 9 from https://doi.org/10.1101/2021.05.29.445137