Alliance for Pandemic Preparedness

October 1, 2020

SARS-CoV-2 Seroprevalence among a Southern U.S. Population Indicates Limited Asymptomatic Spread under Physical Distancing Measures

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  • The seroprevalence of anti-SARS-CoV-2 IgG among people accessing health care for reasons other than COVID-19 symptoms in a low-density, suburban and rural population in North Carolina was 0.8% (24 of 2973) of outpatients and 0.7% (10 of 1449) of inpatients. Participants were sampled between March and June 2020, when state restrictions and physical distancing mandates were in place. Serological testing was performed with the Abbott SARS-CoV-2 IgG assay. The authors state that the low prevalence suggests that shelter-in-place mandates and physical distancing practices may have limited asymptomatic spread.

Barzin et al. (Sept 29, 2020). SARS-CoV-2 Seroprevalence among a Southern U.S. Population Indicates Limited Asymptomatic Spread under Physical Distancing Measures. MBio. https://doi.org/10.1128/mBio.02426-20