Alliance for Pandemic Preparedness

December 2, 2020

Differential Effects of Antiseptic Mouth Rinses on SARS-CoV-2 Infectivity in Vitro

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[Preprint, not peer reviewed] Molecular experiments of several commercially available mouth rinses and antiseptics (Listerine, chlorhexidine gluconate, povidone-iodine, and Colgate Peroxy) found that all products inactivated replication of competent SARS-CoV-2 viruses and pseudotyped viruses expressing spike proteins. The prolonged effect of mouth rinse induced cytotoxicity may impact anti-viral activity. 

Xu et al. (Dec 1, 2020). Differential Effects of Antiseptic Mouth Rinses on SARS-CoV-2 Infectivity in Vitro. Pre-print downloaded Dec 2 from https://doi.org/10.1101/2020.12.01.405662