Alliance for Pandemic Preparedness

December 21, 2020

Broad Cross-National Public Support for Accelerated COVID-19 Vaccine Trial Designs

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Results from a cross-national survey conducted in Australia, Canada, Hong Kong, New Zealand, South Africa, Singapore, the UK, and the US in May 2020 (n = 5920) showed that most respondents preferred for scientists to conduct accelerated trials (human challenge trials, 75%; Phase II/III safety, immunogenicity, and efficacy integrated trials, 63%) over traditional vaccine trials for COVID-19. Respondents were presented with hypothetical studies, and generally understood the key differences and ethical trade-offs between the designs. This support was consistent across geographic and demographic subgroups.

Broockman et al. (Dec 14, 2020). Broad Cross-National Public Support for Accelerated COVID-19 Vaccine Trial Designs. Vaccine. https://doi.org/10.1016/j.vaccine.2020.11.072