Alliance for Pandemic Preparedness

January 27, 2021

Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

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Diagnosis of a schizophrenia spectrum disorder was significantly associated with increased risk of 45-day mortality among adults who tested positive for SARS-CoV-2, after adjusting for demographic and medical risk factors (OR=2.7). The retrospective cohort study enrolled 7,348 individuals at a large medical system in New York, 75 (1%) of whom had a history of a schizophrenia spectrum illness, 564 (8%) who had a history of a mood disorder, and 360 (5%) with a history of an anxiety disorder. Diagnoses of mood (OR=1.14) and anxiety disorders (OR=0.96) were not associated with mortality after adjustment. 

Nemani et al. (Jan 27, 2021). Association of Psychiatric Disorders With Mortality Among Patients With COVID-19. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2020.4442