Alliance for Pandemic Preparedness

August 26, 2020

SARS-CoV-2 Phylodynamics Differentiates the Effectiveness of Non-Pharmaceutical Interventions

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  • [pre-print, not peer-reviewed] By combining phylogenetic data of 5,198 SARS-CoV-2 genomes with the timing of non-pharmaceutical interventions in 57 countries, Rasigade et al. found that home containment and education lockdown had the largest independent impacts on preventing transmission and were predicted to reduce the reproduction number by 35% and 26%, respectively. However, in contexts with a reproduction number >2, the authors conclude that no individual intervention is sufficient to stop the epidemic and increasingly stringent intervention combinations may be required.

Rasigade et al. (Aug 26, 2020). SARS-CoV-2 Phylodynamics Differentiates the Effectiveness of Non-Pharmaceutical Interventions. Pre-print downloaded Aug 26 from https://doi.org/10.1101/2020.08.24.20180927