May 6, 2020

Test Agreement Between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 Assays at High Cycle Threshold Ranges

Category: Article Summary

Topic: Testing and Treatment

• Broder et al. compared the positive test agreement between the Roche cobas 6800 assay and the Cepheid GeneXpert Xpress SARS-CoV-2 assay. Thirty-five nasopharyngeal samples with low viral loads (cycle threshold values >30) from the cobas 6800 were run on the GeneXpert platform. The close agreement between the two tests conducted on samples with low viral concentration indicates that the two assays could be used interchangeable in accordance with testing algorithms. 

Broder et al. (May 5, 2020). Test Agreement Between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 Assays at High Cycle Threshold Ranges. Pre-print downloaded May 6 from https://doi.org/10.1101/2020.05.05.078501