Alliance for Pandemic Preparedness

May 15, 2020

Rapid Implementation of Real-Time SARS-CoV-2 Sequencing to Investigate Healthcare-Associated COVID-19 Infections

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  • Using a sequencing method with a sample-to-sequence delay of less than 24 hours, paired with a reporting system that integrates these genomic data with epidemiological data, Meredith et al. identified both hospital and community clusters among patients from a UK hospital. In addition to detecting cryptic transmission events, this real-time genomic surveillance approach was used to inform infection control and patient safety practices.   

Meredith et al. (May 15, 2020). Rapid Implementation of Real-Time SARS-CoV-2 Sequencing to Investigate Healthcare-Associated COVID-19 Infections. Pre-print downloaded May 15 from https://doi.org/10.1101/2020.05.08.20095687