May 18, 2020

Establishment of an African Green Monkey Model for COVID-19

Category: Article Summary

Topic: Testing and Treatment

• African green monkeys can be used as an animal mode for SARS-CoV-2 infection. African green monkeys experience high levels of SARS-CoV-2 replication and develop pronounced respiratory disease following a much lower and more natural dose of SARS-CoV-2 than has been employed in other non-human primate studies. The heterologous response of African green monkeys along with the ability to collect tissues and longitudinal samples permits a detailed study of pathogenesis and host immunity to COVID-19. 

Woolsey et al. (May 17, 2020). Establishment of an African Green Monkey Model for COVID-19. Pre-print downloaded May 18 from https://doi.org/10.1101/2020.05.17.100289