Alliance for Pandemic Preparedness

June 11, 2020

Rates of Maternal and Perinatal Mortality and Vertical Transmission in Pregnancies Complicated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Co-V-2) Infection: A Systematic Review

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  • Huntley et al. conducted a systematic review of 13 studies with a total sample size of 538 individuals to ascertain pregnancy complications of SARS-CoV-2 infection. Maternal ICU admission occurred in 3% of cases (8/263, 95%CI 1.6-5.9%) and maternal critical disease in 1.4% (3/209, 95%CI 0.5-4.1%). No maternal deaths were reported (0/348). The neonatal death rate was 0.3% (1/313, 95%CI 0.1-1.8%). No vertical transmission was reported (0/310).  

Huntley et al. (June 9, 2020). Rates of Maternal and Perinatal Mortality and Vertical Transmission in Pregnancies Complicated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Co-V-2) Infection: A Systematic Review. Obstetrics and Gynecology. https://doi.org/10.1097/AOG.0000000000004010