Alliance for Pandemic Preparedness

June 12, 2020

Genetic Cluster Analysis of SARS-CoV-2 and the Identification of Those Responsible for the Major Outbreaks in Various Countries

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  • Phylodynamic analysis of 247 genomic sequences available by early March identified four genetic clusters, defined as super-spreader clusters (SSs), which were found to be responsible for the major outbreaks that followed. Ninety percent of an additional 1,539 genome sequences reported from early March onwards were found to belong to these SSs, with SS4 (responsible for the outbreak in Europe) being the most common (56%).  

Yang et al. (Dec 1, 2020). Genetic Cluster Analysis of SARS-CoV-2 and the Identification of Those Responsible for the Major Outbreaks in Various Countries. Emerging Microbes & Infections. https://doi.org/10.1080/22221751.2020.1773745