Alliance for Pandemic Preparedness

June 22, 2020

Reconstruction of Transmission Pairs for Novel Coronavirus Disease 2019 (COVID-19) in Mainland China: Estimation of Super-Spreading Events, Serial Interval, and Hazard of Infection

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  • Xu et al. analyzed 643 transmission clusters from 1,407 transmission pairs in mainland China and identified 34 primary cases as super-spreaders and 5 super-spreading events that occurred within households.  
  • The median duration between symptom onset of primary and secondary cases was 5.0 days (IQR 1.5-8.5) for household transmissions and 5.2 days (1.6-8.8) for non-household transmissions. The risk of being infected outside of households was higher for those age 18 to 64 years, whereas the risk of being infected within households was higher for younger and older people.  

Xu et al. (June 18, 2020). Reconstruction of Transmission Pairs for Novel Coronavirus Disease 2019 (COVID-19) in Mainland China: Estimation of Super-Spreading Events, Serial Interval, and Hazard of Infection. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa790