Alliance for Pandemic Preparedness

July 14, 2020

Investigation and Serologic Follow-Up of Contacts of Early Confirmed Case-Patient with COVID-19, United States

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  • A contact investigation for an early confirmed COVID-19 case from Washington State identified 50 contacts, none of whom had evidence of SARS-CoV-2 infection through 6 weeks of follow-up. All contacts were monitored daily for 14 days following exposure. Eight developed symptoms but tested negative via rRT-PCR. Thirty-eight contacts underwent voluntary enhanced contact investigation, revealing varying degrees of unprotected face-to-face interactions with the case-patient. Negative rRT-PCR and serologic followup collected approximately 6 weeks post exposure suggest no evidence of secondary transmission. 

Chu et al. (May 29, 2020). Investigation and Serologic Follow-Up of Contacts of Early Confirmed Case-Patient with COVID-19, United States. Emerging Infectious Diseases. https://doi.org/10.3201/eid2608.201423