Alliance for Pandemic Preparedness

April 14, 2021

Detection of SARS-CoV-2 Specific IgA in the Human Milk of COVID-19 Vaccinated Lactating Health Care Workers

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  • [Pre-print, not peer-reviewed] SARS-CoV-2 specific IgA and IgG were detected in milk and plasma samples from 22 lactating healthcare workers who had received either the Moderna or Pfizer-BioNTech vaccines, with peak levels occurring 7-10 days after the second dose. Samples were collected prior to vaccination, after the first dose, and after the second dose in a prospective observational study. The authors suggest these antibodies may be transferred to infants during nursing, and future studies should examine the duration of this immune response and the clinical significance for infants.

Valcarce et al. (Apr 13, 2021). Detection of SARS-CoV-2 Specific IgA in the Human Milk of COVID-19 Vaccinated Lactating Health Care Workers. Pre-print downloaded Apr 14 from https://doi.org/10.1101/2021.04.02.21254642