Alliance for Pandemic Preparedness

May 6, 2021

Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers

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  • The Pfizer-BioNTech vaccine was associated with a 93% lower incidence of symptomatic SARS-CoV-2 infection and 86% lower incidence of asymptomatic infection more than 7 days after the second dose in a retrospective cohort of healthcare workers (HCWs) in Israel (n=6,710). The median follow-up period was 63 days. While vaccination was associated with older age and male sex, a sensitivity analysis using propensity score matching found similar results. HCWs with prior SARS-CoV-2 infection were excluded from the study.

Angel et al. (May 6, 2021). Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers. JAMA.  https://jamanetwork.com/journals/jama/fullarticle/2779853