October 5, 2020
A One-Minute Blood Test to Monitor Immune Responses in COVID-19 Patients and Predict Clinical Risks of Developing Moderate to Severe Symptoms
[Preprint, not peer-reviewed] A nanoparticle-enabled blood test could detect a statistically significant differences in immune response between samples collected from COVID-19 patients with no or mild symptoms (n=38) and those with moderate/severe symptoms (n=115), with results available in <1 minute. The authors conclude this new rapid test may be used as a point-of-care clinical tool…
Survival of SARS-CoV-2 and Influenza Virus on the Human Skin: Importance of Hand Hygiene in COVID-19
Survival time of SARS-CoV-2 on human skin was significantly longer than that of influenza A virus (9.0 hours vs. 1.8 hours). Exposure of both viruses to 80% ethanol while on the skin surface, in the context of droplets from a cough or sneeze, inactivated both viruses within 15 seconds of exposure, indicating appropriate hand hygiene…
COVID-19 Literature Situation Report Oct. 5, 2020
Approximately three-quarters of people who required hospitalization for COVID-19 reported at least one lingering symptom or effect 3 months after their symptoms began. The most frequently reported effects were reduced quality of life (51%) and shortness of breath (50%).
October 2, 2020
COVID‐19 in Seattle—Early Lessons Learned
An overview of Seattle’s early experience with the COVID-19 response from 6 regional hospitals revealed coordination between many aspects of the healthcare system, including EMS, hospitals and health systems, outpatient networks, public health officials, and government leaders. Seattle implemented triage processes, continuously updated PPE guidelines and isolation measures, increased the availability of testing, and is…
Diagnostic Accuracy of Web-Based COVID-19 Symptom Checkers: Comparison Study (Preprint)
An evaluation of 10 different web-based COVID-19 symptom checkers found that the number of COVID-19 cases that were assessed correctly varied considerably between different checkers, with Symptoma performing the best. The study assessed 50 COVID-19 case reports along with 410 non-COVID-19 controls and found that only two symptom checkers achieved a good balance between sensitivity…
COVID-19 and Parent Intention to Vaccinate Their Children Against Influenza
Changes in influenza vaccination intentions for 2020 differed significantly between parents whose children received the 2019 influenza vaccine compared to those whose children did not. Among parents whose children did not receive the 2019 vaccine, 34% reported that the COVID-19 pandemic made them less likely to have their child receive the 2020 vaccine. Among those…
COVID-19 Resilience for Survival: Occurrence of Domestic Violence During Lockdown at a Rural American College of Surgeons Verified Level One Trauma Center
There was a statistically significant increase in domestic violence assaults during the COVID-19 lockdown, particularly during the period after school closures, according to a retrospective review of all emergency department patients who presented to an American College of Surgeons verified rural level one trauma center. The increase in cases was observed particularly among white males,…
Increased Dengue Transmissions in Singapore Attributable to SARS-CoV-2 Social Distancing Measures
Social distancing policies in response to the COVID-19 pandemic in Singapore were temporally associated with a 37% increase in the number of dengue cases from baseline in a model controlling for climatic variables associated with mosquito abundance. The authors hypothesize that people may be more likely to be bitten in homes that are often naturally…
Increased Proportion of Physical Child Abuse Injuries at a Level I Pediatric Trauma Center during the Covid-19 Pandemic
The proportion of patients treated for traumatic injuries caused by physical child abuse at the Johns Hopkins Children’s Center during the COVID-19 pandemic was significantly higher compared to the previous two years. During the COVID-19 period, the median age of patients with injuries due to physical child abuse was 11.5 months, and 38% were male….
Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection
A retrospective study of 22 asymptomatic patients infected with SARS-CoV-2 and 234 symptomatic patients with COVID-19 who were hospitalized in Hangzhou, China found that asymptomatic patients tended to be younger (28 years vs. 48 years), female (77% vs 36%), and had fewer coexisting diseases (5% vs 38%) than symptomatic patients. Dai et al. (Sept 19,…
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