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May 11, 2021
Characteristics of Patients Discharged and Readmitted after COVID-19 Hospitalisation within a Large Integrated Health System in the United States
The 30-day readmission rate for patients admitted to hospital with COVID-19 among patients who belong to an integrated healthcare system (Kaiser Permanente) was 8% (n=166) in a retrospective cohort of 2,180 patients between April to July 2020. 58% of readmissions were respiratory-related and occurred a median of 5 days after discharge. Chronic pulmonary disease and…
Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium
Neurological manifestations were found in 82% of patients hospitalized with COVID-19 in a cohort study across 2 consortia of patients from 13 countries (n=3,744). The most common self-reported symptoms included headache (37%) and loss of smell or taste (26%), while the most prevalent neurological signs and/or syndromes were acute encephalopathy (49%), coma (17%), and stroke…
Demographic and Social Factors Associated with COVID-19 Vaccination Initiation Among Adults Aged =65 Years — United States, December 14, 2020–April 10, 2021
79% of US older adults (aged ≥65 years, n>42 million) have received at least 1 dose of a COVID-19 vaccine as of April 10, 2021. On average, counties with low vaccination rates (<50% of older adults) compared with counties with high vaccination rates (≥75% of older adults) had higher percentages of older adults who do…
Cerebral Venous Thrombosis and Portal Vein Thrombosis a Retrospective Cohort Study of 537913 COVID-19 Cases
[Pre-print, not peer-reviewed] Risk of diagnosis for cerebral venous thrombosis (CVT) and portal vein thrombosis (PVT) within 2 weeks of a COVID-19 diagnosis was 6.6-fold higher and 7.4-fold higher, respectively, compared to receiving a COVID-19 mRNA vaccine according to a retrospective study of administrative data in the US. Researchers compared patients with a COVID-19 diagnosis…
SARS-CoV-2 Rapid Antigen Test: High Sensitivity to Detect Infectious Virus
Overall sensitivity of the Panbio rapid antigen test was 71.8% and the sensitivity of the Orient Gene rapid antigen tests was 79.5% for the detection of 156 PCR-confirmed SARS-CoV-2 positive samples. Tested against a panel of PCR-confirmed negative samples, the Panbio test achieved 100% specificity (130 of 130 negative samples) and the Orient Gene test…
A New SARS-CoV-2 Variant Poorly Detected by RT-PCR on Nasopharyngeal Samples with High Lethality
[Pre-print, not peer-reviewed] Patients confirmed by viral sequencing to be infected with a novel SARS-CoV-2 variant first described in France (assigned lineage B.1.616) (n=34) were less likely to test positive on their first PCR test (15% vs 97%) and more likely to die within 28 days (44% vs 16%) compared to patients infected with variants…
Description of a University COVID-19 Outbreak and Interventions to Disrupt Transmission Wisconsin August – October 2020
[Pre-print, not peer-reviewed] Genomic surveillance of SARS-CoV-2 cases from Dane County, Wisconsin did not find evidence of onward community transmission from an outbreak at the University of Wisconsin (UW)-Madison that occurred during the first weeks of school reopening. During the outbreak, a large cluster of cases were identified in two residence halls, after which UW-Madison…
Asymptomatic Individuals Positive for Anti-SARS-CoV-2 Antibodies Negative on Molecular Swab
Only 1% (n=212) of over 16,000 frontline workers developed detectable anti-SARS-CoV-2 antibodies during screening in Italy from May to June 2020. Among antibody-positive individuals, only one tested positive for SARS-CoV-2 RNA under a protocol that required antibody-positive participants to be given a PCR test. The authors suggest that performing a PCR test on antibody-positive participants…
May 10, 2021
The Role of Media Sources for COVID-19 Information on Engaging in Recommended Preventive Behaviors among Medicare Beneficiaries Aged ≥ 65 Years
Most participants (59%) in a survey of Medicare beneficiaries over age 65 (n = 8,050) administered between June and July 2020 reported relying on traditional news sources (TV, radio, websites, newspapers) for COVID-19 information; other less commonly reported sources included healthcare providers (11%), government officials (11%), webpages/internet (9%), friends/family members (9%), and social media (1%)….
Lives versus Livelihoods? Perceived Economic Risk Has a Stronger Association with Support for COVID-19 Preventive Measures than Perceived Health Risk
Perceptions of risk of suffering from economic loss due to the pandemic were associated with COVID-19 mitigation behavior and support for strict containment measures, while perceptions of health risks had variable effects on behaviors and support, in a cross-sectional study with data collected in 24 countries (N = 25,435). Survey results suggest that globally, respondents tended to…
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