Alliance for Pandemic Preparedness

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March 13, 2020

A Novel Approach for a Novel Pathogen: using a home assessment team to evaluate patients for 2019 novel coronavirus (SARS-CoV-2)

This report summarizes the innovative approach of using home assessment to provide real-time clinical evaluation of patients who do not require emergency medical care or hospitalization, a process originally developed for the 2014 Ebola response by the Harborview Medical Center and Public Health Seattle King County. This tool benefits both the public health and clinical…


Potential Presymptomatic Transmission of SARS-CoV-2, Zhejiang Province, China, 2020

After investigating a 2-family cluster of persons infected with COVID-19 in Zhejiang Province, China, the authors suggest that infection resulted from contact with a potentially pre-symptomatic traveler from the city of Wuhan.  Tong et al. (Mar 9, 2020). Potential Presymptomatic Transmission of SARS-CoV-2, Zhejiang Province, China, 2020. Emerg Infect Dis. https://doi.org/10.3201/eid2605.200198 


Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020

The authors investigated a cluster of COVID-19 cases associated with a shopping mall in Wenzhou, China to determine possible modes of virus transmission. The results indicate that indirect transmission potentially occurred via virus contaminated objects, aerosolization in a confined space or spread from asymptomatic infected persons.  Cai et al. (Mar 13, 2020). Indirect Virus Transmission…


The time scale of asymptomatic transmission affects estimates of epidemic potential in the COVID-19 outbreak

This study argues for the need to assess both duration and incidence of asymptomatic cases, which can help in evaluating post-pandemic outcomes.  Park et al. (Mar 9, 2020). The time scale of asymptomatic transmission affects estimates of epidemic potential in the COVID-19 outbreak. Pre-print downloaded on Mar 13 from https://doi.org/10.1101/2020.03.09.20033514


Epidemiological and clinical characteristics of COVID-19 in adolescents and young adults

A study of 46 hospitalized COVID-19 patients aged 10 to 35 years indicates that adolescents and young adults may have a longer incubation period, a shorter serial interval and may be more likely to be asymptomatic.  Liao et al. (Mar 10, 2020). Epidemiological and clinical characteristics of COVID-19 in adolescents and young adults. Pre-print downloaded…


A case report of neonatal COVID-19 infection in China

While most studies in the literature so far have not indicated vertical transmission of COVID-19, this study reports a case of neonatal COVID-19 infection in China 36 hours after birth.  Wang et al. (Mar 12, 2020). A case report of neonatal COVID-19 infection in China. Clin Infect Dis. https://doi.org/10.1093/cid/ciaa225


March 12, 2020

Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore

Wong et al describe potential outbreak response measures for tertiary level acute care hospitals preparing for COVID-19.  Wong et al. (Mar 4, 2020). Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore. Canadian Journal of Anesthesia. https://doi.org/10.1007/s12630-020-01620-9 


Detection of Covid-19 in Children in Early January 2020 in Wuhan, China

This retrospective analysis of 366 children hospitalized in Wuhan early in the COVID-19 outbreak found that the most frequent pathogen identified was influenza A. 6 patients tested positive for COVID-19, presenting with moderate-to-severe symptoms. The findings indicate the COVID-19 infections in children were occurring early in the epidemic.  Liu et al (Mar 12, 2020). Detection…


Coronavirus Disease 2019 (COVID-19): Protecting Hospitals From the Invisible

Klompas emphasizes the need for hospitals to have more aggressive policies on respiratory hygiene and bolstering restrictions on patients, visitors, and health care workers to prevent further spread of COVID-19. Klompas (Mar 11, 2020). Coronavirus Disease 2019 (COVID-19): Protecting Hospitals From the Invisible. Annals of Internal Medicine. Article available here


How Should U.S. Hospitals Prepare for Coronavirus Disease 2019 (COVID-19)?

The authors describe detailed strategies for hospitals to consider when developing their preparedness plans for COVID-19.  Chopra et al. (Mar 11, 2020). How Should U.S. Hospitals Prepare for Coronavirus Disease 2019 (COVID-19)? Annals of Internal Medicine. Article available here



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