Article Summary
June 9, 2021
Exposures Associated with SARS-CoV-2 Infection in France: A Nationwide Online Case-Control Study
SARS-CoV-2 infection risk was associated with having frequented bars and restaurants (OR=1.95) or attending private gatherings (aOR=1.57), according to a multivariate analysis of an online survey administered in France to SARS-CoV-2-infected adults (n=3,426). Survey participants were matched to non-infected controls (n=1713) from October to November by age, sex, population density, and time period. Having one…
June 8, 2021
Reporting of Infectious Diseases in the United States During the COVID-19 Pandemic
Analysis of CDC surveillance data showed an increase in COVID-19 cases that coincided with a decrease in weekly reporting of other infectious diseases. Between 2019 and 2020, reporting of respiratory diseases declined by 51%, injection drug use-associated diseases by 47%, vector borne disease by 44%, and food/waterborne disease by 40%. Reporting of sexually transmitted diseases…
Changes in Methadone Program Practices and Fatal Methadone Overdose Rates in Connecticut during COVID-19
A statewide survey of opioid treatment programs (OPTs) in Connecticut found no increases in methadone-involved fatalities relative to other opioid-involved fatalities, despite dramatic changes in practices as a result of the COVID-19 pandemic. As a result of multiple programmatic changes, the percentage of patients receiving 28-day take-home doses for methadone treatment increased from 0.1% to…
Passing the Test: A Model-Based Analysis of Safe School-Reopening Strategies
A SARS-CoV-2 transmission model simulating an average US elementary and high school classroom found that over an 8-week quarter, asymptomatic weekly screening combined with an A/B schedule generally had the greatest reduction in in-school transmission. Vaccination of staff greatly reduced transmission, but only among staff. Reductions in transmissions varied depending on local SARS-CoV-2 incidence and…
Calculating the Impact of COVID-19 Pandemic on Child Abuse and Neglect in the U.S.
An estimated 60,791 fewer average monthly investigations of child abuse and neglect (CAN) were observed in New York City, New Jersey, Wisconsin and Florida after the pandemic began, according to an analysis of administrative child welfare data in the 4 jurisdictions from January 2013 to December 2020. The corresponding potential lifetime economic impact was estimated…
Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children
29% of pediatric US COVID-19 patients aged ≤18 years (n=43,465) had at least one underlying medical condition, according to an analysis of data collected from more than 800 US hospitals from March 2020 to January 2021. The most common diagnosed conditions were asthma (10%), neurodevelopmental disorders (4%), anxiety and fear-related disorders (3%), depressive disorders (3%),…
Long-COVID Following Mild SARS CoV-2 Infection Characteristic T Cell Alterations and Response to Antihistamines
[Pre-print, not peer-reviewed] “Long COVID” patients with persistent symptoms (mean symptom duration 269 days) treated with histamine receptor antagonists (HRA) (n=25) reported an average reduction in symptom burden by 60%. 20% reported complete symptom resolution, 52% experienced some improvement, and 6 reported no change with a mean time to response of 30 days. By contrast,…
Neutralization against B.1.351 and B.1.617.2 with Sera of COVID-19 Recovered Cases and Vaccinees of BBV152
[Pre-print, not peer-reviewed] Sera from individuals fully vaccinated with the inactivated virus SARS-CoV-2 vaccine Covaxin (n=17) showed a 3-fold reduction in neutralizing activity against the B.1.351 (Beta) and B.1.617.2 (Delta) variants of concern compared with the parent D614G variant. Similarly, sera from individuals recovered from COVID-19 showed a 3-fold and 5-fold reduction in neutralizing activity…
Association between Previous Infection with SARS CoV-2 and the Risk of Self-Reported Symptoms after MRNA BNT162b2 Vaccination: Data from 3,078 Health Care Workers
An online questionnaire among healthcare workers vaccinated with the Pfizer-BioNTech vaccine in Italy (n=3,078) found that participants with prior SARS-CoV-2 infection (n=396) had a 3-fold higher risk of moderate systemic symptoms (MSS) after the first dose, but had a 30% lower risk of symptoms after the second dose. MSS was defined as symptoms that either…
Decreases in COVID-19 Cases, Emergency Department Visits, Hospital Admissions, and Deaths Among Older Adults Following the Introduction of COVID-19 Vaccine — United States, September 6, 2020–May 1, 2021
The rate ratios for COVID-19 incidence, emergency department (ED) visits, hospitalizations, and deaths comparing adults aged ≥65 years (≥70 years for hospitalizations) to adults aged 18-49 years during a 2-week period in April 2021 declined by 40%, 59%, and 65%, respectively compared to a pre-vaccination period in November to December 2020. The authors conclude that…
Previous page Next page