Article Summary
February 19, 2021
Years of Life Lost to COVID-19 in 81 Countries
An estimated 20.5 million years of life have been lost as a result of COVID-19-attributable deaths globally. As of January 6, 2021, years of life lost (YLL) in heavily affected countries, including the United States, are 2–9 times the average losses from seasonal influenza. Three quarters of the YLL result from deaths in ages below…
Provisional Life Expectancy Estimates for January through June, 2020
Provisional life expectancy at birth in the United States reached its lowest level since 2006 in the first six months of 2020, with the life expectancy of the Hispanic population reaching a level lower than any in its recorded history. The life expectancy for both the total population (77.8 years) and for males (75.1) was…
Trends in Use of Telehealth Among Health Centers During the COVID-19 Pandemic — United States, June 26–November 6, 2020
30% of healthcare visits at 1,382 Health Resources and Services Administration-funded health centers occurred via telehealth between June 26 and November 6, 2020. Telehealth visits declined as the number of new COVID-19 cases decreased but plateaued as the number of cases increased. Health centers in the South and rural areas consistently reported the lowest average…
Indirect Acute Effects of the COVID-19 Pandemic on Physical and Mental Health in the UK: A Population-Based Study
A review of electronic health records from a database that includes health information for >10 million individuals in the UK found a substantial reduction in primary care contacts for both acute physical and mental conditions in the four months following the introduction of movement restrictions to prevent transmission of SARS-CoV-2. The largest relative reductions when…
Effect of SARS-CoV-2 Infection during the Second Half of Pregnancy on Fetal Growth and Hemodynamics: A Prospective Study
Mild COVID-19 among pregnant people may not contribute to higher risk of developing fetal growth restriction, according to a single-center case-control analysis. Researchers monitored fetal growth and other factors in 49 pregnancies in patients with mild PCR+ cases diagnosed at a median of 31 weeks gestation to a control group of pregnant people who tested…
COVID-19 Prevalence and Mortality Among Schizophrenia Patients: A Large-Scale Retrospective Cohort Study
A large-scale retrospective cohort study in Israel found that individuals with schizophrenia (n = 25,539) were twice as likely to be hospitalized for COVID-19 (OR = 2.2), even after controlling for sociodemographic and clinical risk factors (OR = 1.9). They were also three times more likely to experience COVID-19 mortality (OR = 3.3) compared to…
HIV-1 Infection Does Not Change Disease Course or Inflammatory Pattern of SARS-CoV-2-Infected Patients Presenting at a Large Urban Medical Center in New York City
People living with HIV (PWH) with COVID-19 were more likely to be admitted from the emergency department when compared to patients without HIV (91% vs 71%), according to a retrospective cohort study in New York. After admission, there was no statistically significant difference in 30-day mortality rate or mechanical ventilation rate. Clinical characteristics, including age,…
Clinical and Laboratory Findings in Patients with Potential SARS-CoV-2 Reinfection, May-July 2020
A clinical and laboratory investigation of potential SARS-CoV-2 reinfection reported to CDC by clinicians in the US did not confirm any cases of reinfection within 90 days of the initial infection, supporting current CDC guidance about retesting for people recovered from COVID-19. Among 73 potential reinfection patients with available records, 70% of patients either had…
Assessment of S1, S2 and NCP-Specific IgM, IgA, and IgG Antibody Kinetics in Acute SARS-CoV-2 Infection by a Microarray and Twelve Other Immunoassays
A study examining antibody kinetics of multiple immunoglobulins in patients hospitalized with acute SARS-CoV-2 infection showed that nucleocapsid protein (NCP)-specific IgA and IgG antibodies are detected earlier, while higher spike (S)1-specific IgA antibody levels occur in severely ill patients. The analysis was conducted using a microarray, eleven different commercial immunoassays (ELISA and CLIA), and one…
First Month of COVID-19 Vaccine Safety Monitoring — United States, December 14, 2020–January 13, 2021
Both the Moderna and Pfizer vaccines had an acceptable safety profile, according to an analysis of the Vaccine Adverse Event Reporting System (VAERS). A total of 13,794,904 COVID-19 vaccine doses were administered in the U.S from December 14, 2020 to January 13. There were 6,994 reports of COVID-19–associated adverse events to VAERS during the period,…
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