Alliance for Pandemic Preparedness

COVID-19 Literature Situation Report

COVID-19 Literature Situation Report is a daily (M-F) newsletter that provides a succinct summary of the latest scientific literature related to the COVID-19 pandemic.

The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.

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April 5, 2021

COVID-19 Literature Situation Report April 5, 2021

Spike-specific IgG antibody levels and ACE2 antibody binding inhibition responses were similar between healthcare workers in California who had been previously infected with SARS-CoV-2 and received a single dose of the Pfizer-BioNTech vaccine and those who had no prior infection and had received both vaccine doses.


April 2, 2021

COVID-19 Literature Situation Report April 2, 2021

In a Wisconsin state prison, 79% of the incarcerated population and 3% of staff members contracted SARS-CoV-2 within 8 weeks after the prison received six newly transferred persons who were not initially identified to be SARS-CoV-2 positive at time of intake. Genome sequencing of 172 cases showed that all specimens belonged to the same lineage.


April 1, 2021

COVID-19 Literature Situation Report April 1, 2021

45% of 5,110 residents from three prisons and 13 jails across four states (all three prisons and 10 jails in Washington State) said they would refuse to receive a COVID-19 vaccine. The most common reason for vaccination refusal was distrust of health care, correctional, or government personnel or institutions. Willingness to be vaccinated was lowest among Black participants, participants aged 18–29 years, and those who lived in jails vs prisons.


March 31, 2021

COVID-19 Literature Situation Report March 31, 2021

In a press release, Pfizer reported that the Pfizer-BioNTech vaccine conferred 100% efficacy against COVID-19 in adolescents age 12-15 with no previous history of SARS-CoV-2 infection. The vaccine also elicited a strong neutralizing antibody response one month after the second dose, and side effects were similar to those observed among participants aged 16-25 in previous trials.


March 30, 2021

COVID-19 Literature Situation Report March 30, 2021

93% of the largest 50 private and 50 public US institutions of higher education offered some in-person teaching for the Fall 2020 semester, 71% of which offered a hybrid reopening structure (≥25% students on campus). Nearly all institutions employing mitigation strategies adopted masking and physical distancing mandates, and over half reduced the density of on-campus housing and classroom density. Over half required entry testing for SARS-CoV-2, and 32% required testing at regular intervals.


March 29, 2021

COVID-19 Literature Situation Report March 29, 2021

The Pfizer/BioNTech and Moderna vaccines were 90% effective at preventing SARS-CoV-2 infection after full immunization and 80% after partial immunization, according to interim estimates among healthcare personnel and essential workers in the US.


March 25, 2021

COVID-19 Literature Situation Report March 25, 2021

Only 1% of over 14,000 nursing home residents in the UK who have received the first dose of either the Pfizer-BioNTech or Oxford-AstraZeneca vaccines reported a positive SARS-CoV-2 PCR test in an observational study from December 2020 to March 2021. 90% of infections occurred within 28 days of the first dose.


March 23, 2021

COVID-19 Literature Situation Report March 23, 2021

Despite low adherence to mitigation measures and low rates of improvements to ventilation systems, minimal in-school transmission of COVID-19 was documented during in-person learning in a school system in Wood County, Wisconsin. Between August and November 2020, only 7 cases among children were attributed to school-based transmission despite high levels of community transmission (none among staff).


March 19, 2021

COVID-19 Literature Situation Report March 19, 2021

School-related COVID-19 incidence was <1% among Florida K-12 students (August-December 2020), were most schools resumed in-person instruction sometime during August 2020. The incidence among students was correlated with community incidence and was highest in smaller counties, districts without mask requirements, and those that reopened earliest after closure in March 2020. Approximately 11% of K-12 schools experienced outbreaks with a median of 6 cases per outbreak. 20% of school outbreaks were associated with activities outside of the classroom.


March 18, 2021

COVID-19 Literature Situation Report March 18, 2021

US parents of children aged 5-12 years who received virtual or combined virtual/in-person instruction were more likely to report both poor parent and child well-being compared to parents of children who received in-person instruction only. Findings are based on a nationwide survey of 1,290 parents, of whom 46% reported their child was receiving virtual instruction only.



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