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Tag: geographic spread
February 17, 2021
Early Introductions and Community Transmission of SARS-CoV-2 Variant B.1.1.7 in the United States
[Pre-print, not peer-reviewed] Using combined data from UK air travel into US airports, SARS-CoV-2 genomic sequencing, and clinical diagnostics, a study found evidence for multiple independent introductions of the SARS-CoV-2 B.1.1.7 variant (first described in the UK) into the US, many of which have led to sustained community transmission. The authors conclude that the high…
Detection of B.1.351 SARS-CoV-2 Variant Strain — Zambia, December 2020
The SARS-CoV-2 variant strain B.1.351 (first described in South Africa) was detected in Zambia in specimens collected from December 16–23, 2020. Among 23 specimens collected during this time, 22 (96%) were the B.1.351 variant, and among those 21 (95%) contained all nine B.1.351 lineage-defining mutations. Specimens with the B.1.351 variant were obtained from people across…
First Identified Cases of SARS-CoV-2 Variant B.1.1.7 in Minnesota — December 2020–January 2021
On January 9, 2021, the Minnesota Department of Health announced the identification of the B.1.1.7 SARS-CoV-2 variant (first described in the UK) in specimens from five people, and on January 25, this variant was found in samples from three additional people. The samples were collected between December 18, 2020 and January 11, 2021 from residents…
February 13, 2021
Before the Surge Molecular Evidence of SARS-CoV-2 in New York City Prior to the First Report
[pre-print; not peer-reviewed] SARS-CoV-2 RNA was found in pooled nasopharyngeal specimens collected from 3,040 people in New York City in the week ending January 25, 2020, suggesting that the virus was present in the city a month before the first officially documented case. The authors were also able to reconstruct phylogenetic relationships between seven complete…
February 11, 2021
Imported SARS-COV-2 Variant P.1 Detected in Traveler Returning from Brazil to Italy
An imported case of the P.1 SARS-CoV-2 variant (also known as the B.1.1.28 or 20J/501Y.V3 variant) was detected in an asymptomatic passenger traveling on an indirect flight from Brazil to Italy on January 17, 2021. The case patient and his family received PCR-negative results at the departure airport in Brazil, and was tested on January…
Novel SARS-CoV-2 Variant Identified in Travelers from Brazil to Japan
A novel SARS-CoV-2 strain was detected in 4 travelers flying from Brazil to Japan on January 2, 2021. Whole genome sequencing suggests the variant descends from the P.1 lineage with 12 nonsynonymous mutations in the receptor-binding domain (RBD) of the spike protein, including the K417T, E484K, and N501Y mutations also present in the B.1.1.7 and…
February 9, 2021
UK coronavirus variant detected at the UW (Message to Seattle students and employees)
[Press release, not peer-reviewed] The B.1.1.7 variant (first described in the UK) was identified in a sample obtained from a University of Washington student in late January 2021. Genetic sequencing occurred as part of the Husky Coronavirus Testing program and was performed on February 8, 2021. The student is doing well and out of their…
February 8, 2021
Genomic Epidemiology Identifies Emergence and Rapid Transmission of SARS-CoV-2 B.1.1.7 in the United States
[Pre-print, not peer-reviewed] Sequencing of 212 B.1.1.7 SARS-CoV-2 variant genomes collected from testing facilities in the U.S. between December 2020 to January 2021 found that while the proportion of B.1.1.7 variants among S gene target failure samples varied by state, detection of the variant had a doubling rate of a little over a week and…
January 15, 2021
Emergence of SARS-CoV-2 B.1.1.7 Lineage — United States, December 29, 2020–January 12, 2021. MMWR
A more highly transmissible variant of SARS-CoV-2, lineage B.1.1.7, has been confirmed to have caused 76 cases in at least 10 states in the US as of January 13, 2021. Models suggest that this variant has potential to drive a new phase of exponential growth in cases in the US, and that even if vaccination…
January 14, 2021
Estimating Internationally Imported Cases during the Early COVID-19 Pandemic
Combined daily COVID-19 prevalence and flight passenger volume were used to estimate importations of SARS-CoV-2 from China. Researchers estimated that Wuhan was the primary source of global case importation from China in early January, but shifted to 18 other Chinese cities as the source in mid-February, particularly for importations to African destinations. The authors estimate…
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