Alliance for Pandemic Preparedness

Result for
Topic: Non-Pharmaceutical Interventions


March 20, 2020

How to improve adherence with quarantine: Rapid review of the evidence

This review on adherence to quarantine found that adherence ranged from 0 to 93%. The most common factors affecting adherence were knowledge about the COVID-19 outbreak, quarantine protocol, social norms, perceived benefits of quarantine and perceived risk of contracting COVID-19 and practicalities of being in quarantine.  This highlights the importance of timely and clear communication…


March 19, 2020

Coronavirus disease-19: Summary of 2,370 Contact Investigations of the First 30 Cases in the Republic of Korea

The study highlights the critical role of contact tracing to contain the COVID-19 outbreak in the early phase in Korea and lists various measures used to complete the contact tracing (i.e. tracking the history of clinic visits, GPS of the cell phones and credit card transaction log).  Korea CDC (Mar 15, 2020). Coronavirus disease-19: Summary…


Effect of large large-scale testing platform in prevention and control of the COVID-19 pandemic: an empirical study with a novel numerical model

Large-scale and standardized clinical testing needs to be implemented in order to maximize the effect of quarantine and minimize the duration and cost.  This empirical study highlights the significance of large-scale testing, as successfully implemented in China, for early prevention and control of COVID-19.  Xie et al. (Mar 15, 2020). Effect of large large-scale testing…


March 18, 2020

Impact of city and residential lockdowns on prevention and control of COVID-19

This article suggests that increasing medical resources, in particular hospital beds, and implementing residential lockdowns in addition to city lockdowns may result in more effective epidemic control.  Shao (March 17, 2020). Impact of city and residential lockdowns on prevention and control of COVID-19. Pre-print downloaded Mar 18 from https://doi.org/10.1101/2020.03.13.20035253 


If Containment is not possible, how do we minimize mortality for COVID-19 and other emerging infectious disease outbreaks?

If containment and social distancing measures cannot be sustained, it may be necessary to move towards herd immunity and allow some SARS-CoV-2 infections to occur, and prioritize interventions that protect vulnerable populations from getting infected.  The authors discuss how school closures potentially reduces infections in low risk groups while shifting the burden to the higher…


March 17, 2020

The positive impact of lockdown in Wuhan on containing the COVID-19 outbreak in China

Lau et al review the positive impacts (significant decrease in the growth rate and increase in the doubling time of COVID-19 cases) that could be attributed to rigorous Chinese lockdown measures, and suggest stringent containment measures should be considered for heavily affected areas to buy time and enable medical facilities to cope with increasing intensive…


March 16, 2020

Impact of self-imposed prevention measures and short-term government intervention on mitigating and delaying a COVID-19 epidemic

The authors emphasize the importance of handwashing, mask-wearing and social distancing as strategies to mitigate and delay the COVID-19 epidemic. Wide spread awareness on these self-imposed prevention measures and government-imposed social distancing can buy time for healthcare systems to prepare for an increasing COVID-19 burden.  Teslya et al. (Mar 12, 2020). Impact of self-imposed prevention…


Impact assessment of non-pharmaceutical interventions against COVID-19 and influenza in Hong Kong: an observational study

Containment and social distancing measures, and changes in population behavior have successfully prevented the spread of COVID-19 in Hong Kong. These measures are less drastic than those used to contain transmission in Wuhan, making them potentially more feasible for other countries.  Cowling et al. (Mar 12, 2020). Impact assessment of non-pharmaceutical interventions against COVID-19 and…


March 11, 2020

The impact of transmission control measures during the first 50 days of the COVID-19 epidemic in China

Tian et al report the impact of travel restriction and national emergency response in delaying the growth and limiting the size of COVID-19 epidemic in China.  The Wuhan shutdown slowed the dispersal of infection to other cities by an estimated 2.9 days and averted hundreds of thousands of cases across China. The most effective interventions…


March 9, 2020

Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China

Wang et al compared epidemiological characteristics across periods and different demographic groups using data on 25,961 laboratory-confirmed COVID-19 cases. They used SEIR model to study the epidemic and evaluate the impact of non-pharmaceutical interventions. With interventions, the effective reproductive number dropped from 3.86 to 0.32 and was estimated to prevent 94.5% infections until February 18….



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